OBAGI Medical Skincare
OBAGI Medical is a dermatologist-developed skincare brand known for its clinically backed formulations targeting various skin concerns, such as hyperpigmentation, aging, and acne. The brand offers a range of prescription-strength and over-the-counter products that promote healthier, more radiant skin. Two of its most well-known lines are Nu-Derm® and CLENZIderm M.D.®, each designed for specific skin concerns.

Nu-Derm® System
Best for: Hyperpigmentation, melasma, age spots, fine lines, and overall skin renewal.
How It Works:
The Nu-Derm® System is a comprehensive skin transformation regimen that helps reduce dark spots, improve skin tone, and enhance skin texture. It is often recommended for moderate to severe hyperpigmentation and is available in both prescription-strength (with 4% hydroquinone) and non-prescription versions (with arbutin as the brightening agent).
Key Ingredients:
- Hydroquinone (Rx only) – A potent skin-lightening agent that reduces hyperpigmentation.
- Tretinoin (often prescribed alongside) – Helps with skin renewal and collagen production.
- Vitamin C (L-Ascorbic Acid) – Brightens skin and provides antioxidant protection.
- AHA/BHA (Glycolic, Lactic, Salicylic Acid) – Exfoliates and promotes cell turnover.
System Includes:
- Gentle Cleanser / Foaming Gel – Cleanses and preps the skin.
- Toner – Balances skin pH and preps for treatment.
- Clear (4% Hydroquinone, Rx required) – Reduces dark spots and pigmentation.
- Exfoderm / Exfoderm Forte – Exfoliates and improves skin texture.
- Blend (4% Hydroquinone, Rx required) – Works with tretinoin for deeper penetration.
- Hydrate – A lightweight moisturizer.
- Sun Shield SPF 50 – Broad-spectrum sunscreen.
Expected Results:
Visible skin improvement within 6–12 weeks, with a full transformation in 18–24 weeks when used consistently. Reduces dark spots, smooths fine lines, and brightens overall skin tone.

CLENZIderm M.D.® System
Best for: Acne-prone, oily, and congested skin.
How It Works:
This three-step acne treatment system uses a unique solubilized 5% Benzoyl Peroxide formula, which allows for deeper penetration into the pores, effectively treating acne at its source.
Key Ingredients:
- 5% Solubilized Benzoyl Peroxide (BPO) – Penetrates pores deeply to kill acne-causing bacteria.
- Salicylic Acid (2%) – Helps exfoliate, unclog pores, and reduce inflammation.
- Menthol & Glycerin – Soothes and hydrates while preventing irritation.
System Includes:
- Daily Care Foaming Cleanser (2% Salicylic Acid) – Removes oil, dirt, and dead skin cells while gently exfoliating.
- Pore Therapy (2% Salicylic Acid) – A toner that unclogs pores and preps skin for treatment.
- Therapeutic Lotion (5% BPO) – Targets acne bacteria and prevents future breakouts.
Expected Results:
- Noticeable reduction in acne within 1–4 weeks.
- Less breakouts, reduced redness, and clearer skin with consistent use.
- Helps prevent future acne by maintaining pore clarity.
Final Thoughts
- Nu-Derm® is ideal for those struggling with hyperpigmentation and signs of aging, offering long-term skin transformation.
- CLENZIderm M.D.® is the go-to system for those battling acne and oily skin, with powerful ingredients targeting breakouts at the source.
- Both systems require consistent use and proper sun protection to see optimal results.
OBAGI Consultations & Prescriptions
OBAGI Consultations
£50 (refundable against a treatment)
Prescription fee (if any prescriptive products are required)
£35 per prescription
Obagi consultations are required as it is a fully prescriptive range which treats these concerns much faster and effectively.
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